Altacor expands as Clinitas gains greater formulary acceptance

December 2011

Altacor, the specialist ophthalmology company, is expanding. It has appointed two experienced product specialists, Alison Jones for the East of England and Ceri Myles for the South East, to help drive awareness of its Clinitas dry-eye treatment products with Hospital Consultants and Primary Care Trusts.

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PROXIMAGEN GROUP PLC
(“Proximagen” or “the Company”)

Proximagen and Altacor sign Collaborative Research and Development Agreement for Proximagen’s 5HT2c programme in Glaucoma

London, UK, 23 November 2011

Proximagen Group plc (AIM: PRX), the rapidly growing company with a principal focus on the treatment of disorders of the central nervous system, and Altacor Limited (“Altacor”), a specialty ophthalmic pharmaceutical company, today announce that they have signed a Collaborative Research and Development Agreement (the “Agreement”). Under the terms of the Agreement Altacor will undertake the research and development of PRX00933, the lead compound from Proximagen’s 5HT2c programme, to treat glaucoma. Altacor also gains an option for exclusive global rights to ophthalmic indications with Proximagen retaining all rights outside of ophthalmology. The financial terms of the Agreement were not disclosed.

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Streaming eyes can be a symptom of 'Dry Eye'

Cambridge, UK, October 2011

Watery eyes, particularly in windy, sunny or dry conditions, can be a symptom of ‘dry eye’ and can also be triggered by many medical conditions and taking certain medications. Cambridge-based Altacor has found that practice nurses are frequently asked for advice about the condition and many are unaware that relief is easy to achieve.

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Spotting the real causes of Dry Eye: Altacor’s Clinitas products have the answer

Cambridge UK, September 2011

If you have uncomfortable or sore eyes you might be suffering from dry eye especially if you spend long periods at a computer. Although this condition is extremely common, it is often disregarded, which can lead to mild and in some cases severe problems with one or both eyes.

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Altacor enhances Dry Eye and Glaucoma development portfolio

Cambridge UK, 26th July 2011

Altacor has gained exclusive worldwide rights from Ophthalmopharma for their two proprietary therapeutic development products Latanoprost CD and Cyclosporin A Prodrug. These licensing agreements are the last in the series of transactions in which Altacor now assumes full responsibility for the entire Ophthalmopharma portfolio of ophthalmic products covering development, Intellectual Property and commercialisation rights.

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Altacor adds nutritional AMD preventative to portfolio

Cambridge UK, 21st April 2011

Altacor has concluded an exclusive worldwide licensing agreement with Ophthalmopharma for the Age Related Macular Degeneration (AMD) nutritional product EYEBAR®. This is the second in a series of transactions between Altacor and Ophthalmopharma in which Altacor will assume responsibility for the entire portfolio of ophthalmic products covering development, IP and commercialisation of the products.

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Altacor broadens portfolio with Intraocular lens (IOL) delivery

Cambridge UK, 14th April 2011

Altacor announces that it has today concluded an exclusive, worldwide licensing agreement with the Swiss based company Ophthalmopharma for its proprietary, preloaded injector for delivery of intraocular lens in cataract and corrective lens replacement surgery (currently known as SOLO®). This is the first in a series of transactions between Altacor and Ophthalmopharma in relation to its entire portfolio of ophthalmic products. Under the terms of the agreement, Altacor has assumed responsibility for all aspects of development, IP and commercialisation of the products.

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New-look Clinitas Soothe is now re-sealable for 12 hours for better economy

Cambridge, April 2011

Clinitas Soothe is a natural, preservative-free eye drop with the UK’s highest concentration of a natural lubricant, sodium hyaluronate. It is available in sterile containers that are safe, convenient and easy to use. Each pack contains 20 individual units each of which can now be used throughout a 12 hour period. Each unit can be opened and re-sealed with confidence thanks to new data confirming that the solution does not support the growth of microorganisms that can cause eye infection. Each unit contains between 8 and 10 drops, sufficient for one day’s use. After removing the lid, it can be inverted and replaced to form a good seal which will not leak. This makes Clinitas Soothe highly economic to use.

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Clinitas Range is now available in Vision Express Stores Nationwide

Cambridge, April 2011

Altacor is pleased to announce the launch of the Clinitas Range in Vision Express. After extensive product trials, the rationale for having a full range of dry eye products covering conditions whether they are mild, moderate, severe or acute or chronic was clear. With the comprehensive Clinitas Range the various presentations of dry eye can be addressed. The Clinitas Range comprises three products Clinitas Hydrate, Clinitas Soothe and Clinitas Ultra 3 which collectively increase, stabilise and restore the three layers of the tear film. The products are easy to apply and good value for money. Clinitas Hydrate is a high performance liquid gel drop that rapidly spreads across the whole eye surface to reduce friction, providing lubrication and comfort particularly overnight or on wakening. The carbomer component boosts the aqueous layer of the tear film and can stay on the eye for up to 8 hours.

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Altacor’s £3.4m funding signals a positive start to 2011

Cambridge, April 2011

Cambridge UK, 8th February 2011 Altacor today announced the closing of the second tranche (£1.9m) of a £3.4m equity fund raising which was led by Clive Austin of NVM Private Equity and included Enterprise Ventures (through its RisingStars Growth Fund)and Beringea, an existing investor.

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